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Friday, October 23, 2026Updated 01:55 UTC

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Researchers develop AI tool to map microRNA binding sites on circular RNAs

Source: Phys.org · Oct 23, 2026 00:20 UTC

Rows of NASA Pleiades supercomputer racks at Ames Research Center — File photo NASA / Dominic Hart · Public domain · Source

The Quick Take

Circular RNAs (circRNAs) are loop-shaped molecules that can influence gene regulation through interactions with microRNAs (miRNAs). This matters because circRNAs can exist as different full-length isoforms, and their back-splice junction (BSJ) connects the two ends of the RNA. Treating a circular RNA like a linear transcript can therefore overlook sequence information near this junction.

Read the full story at Phys.org

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